The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Reuptake Inhibitors: Mechanisms ... • Serotonin Syndrome ... SSRI Withdrawal Syndrome ... Dizziness - Nausea
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Inhibitors(SNRIs): Mechanisms ... Diarrhea, Insomnia, Nausea ... Vomiting Serotonin Syndrome ... gain Incr NE: Nausea
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Mood Stabilizers: Mechanism ... Stevens-Johnson Syndrome ... Systemic effect -> Nausea ... MoodStabilizers #Mechanism
Acquired Immunodeficiency Syndrome (AIDS): Summary of Causes and Ocular Manifestations
 • Molluscum lesions
 • Eyelid Kaposi
Immunodeficiency Syndrome ... AIDS): Summary of Causes ... • Cotton wool spots
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... #CaudaEquina #Syndrome ... #MSK #pathophysiology
RICE: Mechanism of Action
Rest (weight bearing or stressful motion discontinued)
Ice (applied to injury)
Compression (wrap applied to
RICE: Mechanism ... heart) #RICE #Sports ... pathophysiology #mechanism ... #MSK
Shoulder Impingement Syndrome (SIS): Signs and Symptoms

Repetitive Overhead Activity, Scapular Dyskinesis -> Scapulohumeral mechanics become altered
Shoulder Impingement Syndrome ... Scapulohumeral mechanics ... Shoulder Impingement Syndrome ... #Impingement #Syndrome ... signs #symptoms #msk
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles
Note: Some charts show different relative levels of
days long) • Starts ... puberty (unclear mechanisms ... , progesterone causes
Chronic Exertional Compartment Syndrome (CECS)
 • Diagnosis Of CECS requires patient to undergo the same exertional
Exertional Compartment Syndrome ... activity that causes ... signs #symptoms #msk
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
healing time, mechanisms ... Fluoroquinolones - Causes ... #Orthopedics #msk