The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Acquired Immunodeficiency Syndrome (AIDS): Summary of Causes and Ocular Manifestations
 • Molluscum lesions
 • Eyelid Kaposi
• Cotton wool spots ... Complications #ophthalmology
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
LowAnkleSprain #Sports ... #MSK #orthopedics
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
-> Cotton-wool spots ... Retinopathy #Diabetes #ophthalmology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
-> Cotton-wool Spots ... -> Elschnig's Spots ... pathophysiology #ophthalmology
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
conjunctiva) • Bitot's spots ... pathophysiology #ophthalmology
Age Related Macular Degeneration: Pathogenesis and clinical findings

Photoreceptor atrophy 
-> Extracellular debris (drusen) from RPE atrophy/metabolism
- Faded/blind spots ... pathophysiology #ophthalmology
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
> Stiffness is short-lived ... #Degenerative #Comparison ... #Versus #MSK #JointDisease
Hyperopia: Pathogenesis and clinical findings
 • Axial length of eye -> Short axial length of the
length of eye -> Short ... pathophysiology #ophthalmology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
-> Cherry-red spot ... pathophysiology #ophthalmology
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles
Note: Some charts show different relative levels of
days long) • Starts ... pathophysiology #comparison