The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
URT inflammation causes ... severe swelling causes ... Tetanus Toxin -> Spores ... metabolites induce injury ... lymph -> Koplik's spots
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
most commonly injured ... (uncommonly injured ... PTFL is rarely injured ... LowAnkleSprain #Sports ... #MSK #orthopedics
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
Findings Compression/injury ... Tingling, Burning, Stinging ... , Stabbing) - ... MeralgiaParesthetica #MSK
RICE: Mechanism of Action
Rest (weight bearing or stressful motion discontinued)
Ice (applied to injury)
Compression (wrap applied to
Ice (applied to injury ... wrap applied to injured ... heart) #RICE #Sports ... pathophysiology #mechanism #MSK
Posterior Cruciate Ligament (PCL) Injury: Pathogenesis and Clinical Findings
Classification of PCL Iniuries
 • Partial: Translation <
Ligament (PCL) Injury ... Some sort of end ... PCL: The PCL is injured ... PosteriorCruciateLigament #PCL #Injury ... #MSK #Sports #pathophysiology
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
Prolonged shoulder injury ... a stroke that caused ... signs #stages #staging ... #msk
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... pain (shooting, stabbing ... CaudaEquina #Syndrome #MSK
Isolated Anterior Cruciate Ligament (ACL) Injury: Pathogenesis and clinical findings
 • Feeling a "pop"
 • Acute
Ligament (ACL) Injury ... AnteriorCruciateLigament #ACL #Injury ... #MSK #Sports #pathophysiology
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Fluoroquinolones - Causes ... #Orthopedics #msk ... #Staging #pathophysiology