The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis pathophysiology signs symptoms ophthalmology adhesivecapsulitis caudaequina centralretinalartery chronic disruptors fracture frozenshoulder healing hypertensive occlusion orthopedics pagetsdisease retinopathy syndrome
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
hypercoagulable state ... causing localized stasis ... Hypercoagulable state ... -> Cherry-red spot ... retinal edema caused
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
Hypertension Stage ... -> AV nicking Stage ... -> Cotton-wool Spots ... -> Elschnig's Spots ... signs #symptoms #complications
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
a stroke that caused ... ligaments First stage ... side) Second Stage ... movement) Third Stage ... #staging #msk
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... Signs / Symptoms / Complications ... pain (shooting, stabbing ... CaudaEquina #Syndrome #MSK
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... Abnormal Osteoclasts cause ... bone formation MSK ... Nephrolithiasis (Kidney Stones ... signs #symptoms #complications
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Inflammatory Stage ... site Soft Callus Stage ... Fluoroquinolones - Causes ... #Orthopedics #msk ... #Staging #pathophysiology
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