The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
URT inflammation causes ... severe swelling causes ... Tetanus Toxin -> Spores ... lymph -> Koplik's spots ... hepatocellular necrosis & degeneration
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... • Large lumbar degenerative ... pain (shooting, stabbing ... CaudaEquina #Syndrome #MSK
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
a stroke that caused ... ligaments First stage ... side) Second Stage ... movement) Third Stage ... #staging #msk
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Hypertension Stage ... vascular tortuosity Stage ... -> AV nicking Stage ... -> Cotton-wool Spots ... -> Elschnig's Spots
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
Inflammatory and Degenerative ... Lots of fluid, takes ... ESR, RF, ANA) Degenerative ... > Stiffness is short-lived ... Comparison #Versus #MSK
Disc Herniations - Pathogenesis and Complications
• 90% of Lumbar disc herniations happen at L4/5 and L5/S1
•
happen at C6/7 Aging ... ->Degeneration ... complications #msk
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
around the hip • Degeneration ... pathophysiology #causes ... signs #diagnosis #msk
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
hypercoagulable state ... causing localized stasis ... Hypercoagulable state ... -> Cherry-red spot ... retinal edema caused
Mental Status Exam (MSE)
Note: The MSE is a "snapshot" of a patient at a specific time.
You
Mental Status Exam ... (MSE) Note: The ... MSE is a "snapshot ... clothing, appears stated ... , the symptoms caused
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles
Note: Some charts show different relative levels of
days long) • Starts ... follicle (others degenerate ... , progesterone causes