The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle Glaucoma ... present with early glaucoma ... -> crowding of ocular ... resistance to the flow ... pathophysiology #ophthalmology
Age Related Macular Degeneration: Pathogenesis and clinical findings

Photoreceptor atrophy 
-> Extracellular debris (drusen) from RPE atrophy/metabolism
Age Related Macular ... reduces blood flow ... Amsler grid) - Macular ... early disease) #AgeRelated ... pathophysiology #ophthalmology
Aqueous Humor Production and Drainage
 • Provides nutrition, removes wastes, and transports neurotransmitters to the avascular
structural integrity of ocular ... Pathway (~60-80 % of flow ... Schlemm's Canal -> Flows ... ciliary body -> Flows ... Pathophysiology #ophthalmology
Primary Open-Angle Glaucoma: Pathogenesis and Clinical Findings
 • Risk factors -> Incr IOP, Incr age, African-American
Primary Open-Angle Glaucoma ... intra- or peri-ocular ... Primary Open-Angle Glaucoma ... Decr axoplasmic flow ... pathophysiology #ophthalmology
Secondary Glaucoma: Pathogenesis and Clinical Findings
Open-Angle Secondary Glaucoma:
 • Pre-trabecular defect -> Aqueous outflow is obstructed
Secondary Glaucoma ... Open-Angle Secondary Glaucoma ... => Secondary glaucoma ... Decr axoplasmic flow ... pathophysiology #ophthalmology