The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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glaucoma acute aqueoushumor centralretinalartery closedangle diagnosis drainage maculardegeneration occlusion openangle production secondary signs symptoms
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Abnormal blood flow ... due to upstream CRAO ... retinal artery blood flow ... #pathophysiology ... #ophthalmology
Age Related Macular Degeneration: Pathogenesis and clinical findings Photoreceptor atrophy -> Extracellular debris (drusen) from RPE atrophy/metabolism
Age Related Macular ... reduces blood flow ... early disease) #AgeRelated ... MacularDegeneration #pathophysiology ... #ophthalmology
Aqueous Humor Production and Drainage • Provides nutrition, removes wastes, and transports neurotransmitters to the avascular
structural integrity of ocular ... Pathway (~60-80 % of flow ... ciliary body -> Flows ... #Pathophysiology ... #ophthalmology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
-> crowding of ocular ... resistance to the flow ... ClosedAngle #Glaucoma #pathophysiology ... #ophthalmology
Primary Open-Angle Glaucoma: Pathogenesis and Clinical Findings • Risk factors -> Incr IOP, Incr age, African-American
intra- or peri-ocular ... Decr axoplasmic flow ... OpenAngle #Glaucoma #pathophysiology ... #ophthalmology
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