The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
detachment • Red Eye ... Pseudo-hypopyon • Secondary ... glaucoma • Strabismus ... Retinoblastoma #pathophysiology ... #ophthalmology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
present with a red eye ... Occurs in small eyes ... -> crowding of ocular ... #pathophysiology ... #ophthalmology
Periorbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Dacryoadenitis: infection of the lacrimal glands
b. Conjunctivitis: inflammation of the
lacrimal sac, secondary ... Note: Eye exam ... normal: - extra-ocular ... Periorbital #Cellulitis #pathophysiology ... #ophthalmology
Chemical Eye Injury: Pathogenesis and clinical findings
Exogenous chemical to the eye and/or adnexa
 • Ammonia, sodium
Chemical Eye Injury ... chemical to the eye ... the most common acids ... #Ocular #opthalmology ... #pathophysiology
Primary Open-Angle Glaucoma: Pathogenesis and Clinical Findings
 • Risk factors -> Incr IOP, Incr age, African-American
Primary Open-Angle Glaucoma ... intra- or peri-ocular ... central vision #Secondary ... #pathophysiology ... #ophthalmology