The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
to effects of EtOH ... • Withdrawal symptoms ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Psychiatry
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs / Symptoms ... / Complications ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
mortality rates of all psychiatric ... binge-purge subtype #AnorexiaNervosa ... pathophysiology #diagnosis ... #signs #symptoms ... #psychiatry
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms #complications
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
Nervosa: Signs and Symptoms ... related to complications ... pathophysiology #diagnosis ... #signs #symptoms ... #psychiatry
Anorexia Nervosa: Signs and Symptoms
Binge/Purge Subtype - Recurrent (once per week) episodes of binge-eating or purging,
Nervosa: Signs and Symptoms ... irritability #AnorexiaNervosa ... pathophysiology #diagnosis ... #signs #symptoms ... #psychiatry
Alcohol Withdrawal: Clinical Findings and Complications
The onset of alcohol withdrawal generally begins 6-24 hours after the
Clinical Findings and Complications ... Symptoms typically ... >2 days after EtOH ... Pathophysiology #Diagnosis ... #EtOH
Anorexia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: concordance
athletics) #AnorexiaNervosa ... pathophysiology #diagnosis ... #signs #symptoms ... #psychiatry #RiskFactors
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
Bulimia Nervosa: Complications ... BulimiaNervosa #Complications ... pathophysiology #diagnosis ... #signs #symptoms ... #psychiatry