The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Sensitization" to Allergen ... Initial exposure to allergen ... as potentially ... lgE Abs persist
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
Achilles Tendon ... findings • The Achilles ... in the body • Achilles ... rupture of the Achilles ... pathophysiology #msk #orthopedics
Allergic Rhinitis: Pathogenesis and clinical findings

1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Allergic Rhinitis ... Allergy Sensitization ... Plasma Cells -> lgE Abs ... Tissue edema #Allergic
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Production of lgE Abs ... leading to an allergic ... leading to an allergic ... An allergic reaction ... #Allergic #Reactions
Acute Compartment Syndrome
 • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
CompartmentSyndrome #ACS ... pathophysiology #orthopedics