The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis msk signs symptoms allergy immunology fractures acute allergic complications hypersensitivityreaction radiology anaphylaxis bonetumors definitions grades grading hypersensitivity injury
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Penicillin-induced drug reaction ... Dermatitis (ie. reaction ... Allergy #Allergic #Reactions ... #Types #Classification
Open Fractures: Mechanisms, Clinical Features and Complications Gustilo-Anderson Classification: • Type I - Wound <
Gustilo-Anderson Classification ... GustiloAnderson #Classification ... Complications #MSK #Orthopedics
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Classification of ... PelvicRing #Fractures #Classification ... Grades #Grading #Orthopedics
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
constipation • Allergic reaction ... mediated cytotoxic reaction
Allergic Rhinitis: Pathogenesis and clinical findings 1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Primary Reaction ... Secondary Reaction ... after the primary reaction
Necrotizing Fasciitis: Pathogenesis and Clinical Findings #NecrotizingFasciitis #pathophysiology #orthopedics
pathophysiology #orthopedics
Representative X-ray appearance of a primary malignant bone tumor - Ewings Sarcoma • "Interrupted periosteal reaction
Interrupted periosteal reaction
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
StressFractures #msk #orthopedics
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
to an allergic reaction ... causes an immune reaction ... to an allergic reaction ... An allergic reaction ... #Types #Classification
Anaphylaxis: Pathogenesis Anaphylaxis is a Type 1 hypersensitivity reaction While the primary mechanism of anaphylaxis is mast cell
hypersensitivity reaction
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