The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Acute Compartment Syndrome
 • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
Acute Compartment ... local signalling mechanisms ... compartment pressure #Acute ... CompartmentSyndrome #ACS ... pathophysiology #orthopedics
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Anti-Psychotics: Mechanisms ... Block action of ACh ... throughout body (mouth, gut ... bradykinesia/akinesia • Acute ... FirstGeneration #Mechanisms
Second Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
Antipsychotics: Mechanisms ... As such, it is considered ... Antagonism - Block ACh ... Gut, mouth, eyes ... SecondGeneration #Mechanisms
Open Fractures: Mechanisms, Clinical Features and Complications
Gustilo-Anderson Classification:
 • Type I
   - Wound <
Open Fractures: Mechanisms ... Typically "inside out ... Complications #MSK #Orthopedics
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Fracture Healing (and disruptors ... ) • Fracture disrupts ... healing time, mechanisms ... Healing #Stages #Orthopedics ... pathophysiology #diagnosis #disruptors
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... must be ruled out ... bodies, shallow ACD ... Photophobia #Acute
Isolated Anterior Cruciate Ligament (ACL) Injury: Pathogenesis and clinical findings
 • Feeling a "pop"
 • Acute
Cruciate Ligament (ACL ... Feeling a "pop" • Acute ... knee is "giving out ... AnteriorCruciateLigament #ACL