The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Open Fractures: Mechanisms, Clinical Features and Complications
Gustilo-Anderson Classification:
 • Type I
   - Wound <
Typically "inside out ... Open #Fractures #Diagnosis ... Complications #MSK #Orthopedics
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Chlorpromazine ACh ... Block action of ACh ... throughout body (mouth, gut ... #pharmacology #diagnosis
Second Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
As such, it is considered ... Antagonism - Block ACh ... Gut, mouth, eyes ... #pharmacology #diagnosis
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
findings - For diagnosis ... to 25 for new diagnosis ... as if "driven by ... Impulsivity • Blurts out ... Pathophysiology #diagnosis
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Fracture Healing (and disruptors ... ) • Fracture disrupts ... Healing #Stages #Orthopedics ... pathophysiology #diagnosis ... #disruptors