The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
such as peptides ... Ags tagged with ... Opsonization: Abs ... Neutralization: Abs ... pathophysiology #immunology
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
inflammatory cells • ANS ... pathophysiology #immunology
Acute Compartment Syndrome
 • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
CompartmentSyndrome #ACS ... pathophysiology #orthopedics
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
recognizes allergen as ... Allergen-specific lgE Abs ... HypersensitivityReaction #Allergy #Immunology
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Fracture Healing (and disruptors ... ) • Fracture disrupts ... Healing #Stages #Orthopedics ... pathophysiology #diagnosis #disruptors