The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
to effects of EtOH ... • Withdrawal symptoms ... , tachycardia, nausea ... #Pathophysiology ... Diagnosis #Signs #Symptoms
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
hyalinization causes ... BRB breakdown causes ... #Retinopathy #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
lights are a key symptom ... • Significant cause ... most frequent cause ... ClosedAngle #Glaucoma #pathophysiology ... #ophthalmology
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Fracture Healing (and disruptors ... ) • Fracture disrupts ... Fluoroquinolones - Causes ... Healing #Stages #Orthopedics ... #msk #Staging #pathophysiology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
retinal edema caused ... Occlusion #CRAO #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Alcohol Withdrawal: Clinical Findings and Complications
The onset of alcohol withdrawal generally begins 6-24 hours after the
Symptoms typically ... >2 days after EtOH ... dreams, anorexia, nausea ... Alcohol #Withdrawal #Pathophysiology ... #EtOH