The Calgary Guide to Understanding Disease @TheCalgaryGuide
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immunology pathophysiology diagnosis classification definitions hypersensitivity hypersensitivityreaction management reactions signs symptoms treatments type1 typei types
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Sensitization" to Allergen ... Initial exposure to allergen ... after clearance of allergen ... conjunctivitis • Anaphylaxis
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Immunological Target: Allergen ... Hypersensitivity #Allergy ... #Allergic #Reactions
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... and Symptoms Anaphylaxis ... exposure to a likely allergen ... exposure to known allergen ... Angioedema #Anaphylaxis
Anaphylaxis: Treatments (Acute) Additional Info: • IV steroids may be considered for prevention of late phase reactions.
Anaphylaxis: Treatments ... provided, as well as allergy ... Ventolin inhaler #Anaphylaxis
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