The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology hypersensitivityreaction immunology classification diagnosis definitions hypersensitivity reactions complications fractures grading msk pelvicring type1 type2 type3 type4 typei typeiii typeiv
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Immunological Target: Allergen ... Hypersensitivity #Allergy ... #Allergic #Reactions
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
Type I Hypersensitivity ... leading to an allergic ... Sensitization" to Allergen ... Anaphylaxis #TypeI ... #Type1 #HypersensitivityReaction
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... development of allergen-specific ... Allergic reaction ... Initial exposure to allergen ... HypersensitivityReaction #Allergy
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
leading to an allergic ... leading to an allergic ... leading to an allergic ... An allergic reaction ... #Allergic #Reactions
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
Type III Hypersensitivity ... sickness #TypeIII #Type3 ... HypersensitivityReaction #Allergy
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
cyclist) - APC Grade ... 2.5cm - APC Grade ... auto) - LC Grade ... 3 - Type 1 or 2 ... #Grading #Orthopedics
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
Type II Hypersensitivity ... cell surfaces #Type2 ... #Type2 #HypersensitivityReaction ... #Allergy #Immunology
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