The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis classification hypersensitivityreaction immunology allergic definitions msk types complications disruptors fracture grading healing pelvicring stages staging type1 type2 type4
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Penicillin-induced drug reaction ... , Myasthenia Gravis ... , Graves' Disease ... Dermatitis (ie. reaction ... #Reactions #Types
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
of Pelvic Ring Fractures ... - LC Grade ... 2 - Rami fracture ... posterior ilium fracture ... #Grading #Orthopedics
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
Hypersensitivity ... reaction • Type ... An allergic reaction ... #Hypersensitivity ... #Allergy #Allergic
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
Type I Hypersensitivity ... leading to an allergic ... reaction. ... Sensitization" to Allergen ... Initial exposure to allergen
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
Type IV Hypersensitivity ... mediated; exposure to allergen ... development of allergen-specific ... Allergic reaction ... Initial exposure to allergen
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
Type II Hypersensitivity ... antibody-mediated immune reaction ... HypersensitivityReaction #Allergy
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Fracture Healing ... Stage (0-7d) • Fracture ... > Inflammatory reaction ... chondrocytes at fracture ... #Stages #Orthopedics
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