The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis signs symptoms caudaequina disruptors fracture healing hypersensitivityreaction immunology pagetsdisease staging type4 typeiv
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
causes development ... Allergic reaction ... T-Cell activation takes ... Stevens-Johnson Syndrome ... #Immunology #pathophysiology
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... Signs / Symptoms / Complications ... #CaudaEquina #Syndrome ... #MSK #pathophysiology
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... bone formation MSK ... Nephrolithiasis (Kidney Stones ... PagetsDisease #pathophysiology ... signs #symptoms #complications
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Inflammatory Stage ... site Soft Callus Stage ... Fluoroquinolones - Causes ... #Orthopedics #msk ... #Staging #pathophysiology
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