The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
TypeIII #Type3 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
TypeIV #Type4 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
#Type2 #Type2 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
#TypeI #Type1 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
#Anaphylaxis #pathophysiology ... #immunology #diagnosis
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
40% of patients diagnosed ... Agammaglobulinemia #XLinked #pathophysiology ... #immunology
Priapism: Pathogenesis

 - Post-cavernosal venous occlusion -> Post-cavernosal venous drainage is mechanically obstructed e.g. sickle cell
#Priapism #Pathophysiology ... #Urology #Diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Injury #Syndromes #diagnosis ... #pathophysiology ... #orthopedics #neurology
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings

Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
Incontinence #Mixed #Pathophysiology ... Signs #Symptoms #Urology ... #Diagnosis
Varicocele: Pathogenesis and clinical findings
Primary:
 - Anatomically: the left spermatic vein drains into the left renal
#Varicocele #Pathophysiology ... Signs #Symptoms #Urology ... #Diagnosis