The Calgary Guide to Understanding Disease @TheCalgaryGuide
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symptoms signs msk psychiatry complications orthopedics syndrome immunology behavioraldisorder urology vasculitis differential pharmacology acute causes classification criteria hypersensitivityreaction allergic anorexianervosa
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Sensitization" to Allergen ... Initial exposure to allergen ... after clearance of allergen ... #Immunology #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... development of allergen-specific ... Allergic reaction ... Initial exposure to allergen ... #Immunology #pathophysiology
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Hypersensitivity #Allergy ... #Allergic #Reactions ... Classification #Diagnosis
Central Retinal Vein Occlusion (CRVO): Pathogenesis and clinical findings #CentralRetinalVein #Occlusion #CRVO #pathophysiology #ophthalmology #diagnosis #signs #symptoms
Occlusion #CRVO #pathophysiology ... #ophthalmology ... #diagnosis #signs
Allergic Rhinitis: Pathogenesis and clinical findings 1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Allergic Rhinitis ... Allergy Sensitization ... Tissue edema #Allergic ... Rhinitis #Rhinorrhea #pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
exposure to a likely allergen ... exposure to known allergen ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Amblyopia ("Lazy Eye"): Pathogenesis and clinical findings Amblyopia => Interruption of visual stimulation during childhood visual development
Amblyopia #LazyEye #pathophysiology ... #ophthalmology
Posterior Vitreous Detachment: Pathogenesis and clinical findings Separation of the cortical vitreous from the neurosensory retina posterior
Vitreous #Detachment #pathophysiology ... #ophthalmology
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