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The Calgary Guide to Understanding Disease
@TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation -
http://calgaryguide.ucalgary.ca/
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time
diagnosis
signs
symptoms
allergy
hypersensitivityreaction
c5c9deficiency
cascade
complications
extraarticular
henochscholeinpurpura
hsp
humoral
iga
immunity
inflammatory
lupus
manifestations
mucocutaneous
ra
rheumatoidarthritis
dead tissue •
Complement
... destruction), promote
inflammation
... activation of
complement
... #
pathophysiology
... #
immunology
is rare Normal
complement
... response: The
complement
... •
Inflammation
... #
pathophysiology
... #
immunology
activation •
Complement
... tagged with C3
complement
... proliferate and
differentiate
... Humoral #Immunity #
pathophysiology
... #
immunology
manifestations Skin: •
Inflammation
... blood vessels (
vasculitis
... Eyes: • Globe
inflammation
... on CXR • RA
inflammation
... RheumatoidArthritis #RA #
pathophysiology
cells or CTLs ->
Inflammation
... HypersensitivityReaction #Allergy #
Immunology
... #
pathophysiology
IgA
Vasculitis
– ... Activation of
complement
... Leukocytoclastic
vasculitis
... #HSP #IgA #
Vasculitis
... HenochScholeinPurpura #
Pathophysiology
activates the
complement
... HypersensitivityReaction #Allergy #
Immunology
... #
pathophysiology
scaling that extend
inflammation
... -> Incr local
inflammation
... follicles due to
inflammation
... Livedo Reticularis,
Vasculitis
... Manifestations #
pathophysiology
empty