The Calgary Guide to Understanding Disease @TheCalgaryGuide
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complications diagnosis lupus signs symptoms agammaglobulinemia allergy cascade erythematosus gastrointestinal humoral hypersensitivityreaction inflammation inflammatory manifestations mucocutaneous systemic type3 typeiii xlinked
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Continued Innate Immunity ... destruction Acquired Immunity ... #Inflammation #pathophysiology ... #immunology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
Erythematosus (SLE ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Humoral Immunity ... classical pathway (see ... proliferate and differentiate ... #pathophysiology ... #immunology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
the pancreas, Vasculitis ... Erythematosus #SLE ... Complications #pathophysiology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
adaptive humoral immunity ... Agammaglobulinemia #XLinked #pathophysiology ... #immunology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Livedo Reticularis, Vasculitis ... Phenomenon #Lupus #SLE ... Manifestations #pathophysiology
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