The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis retinopathy diabetes pediatrics peds signs symptoms 21hydroxylasedeficiency 21ohd acute chronic closedangle diabetic diabeticketoacidosis dka genetics glaucoma glftap hypertensive keratoconus
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Signs / Symptoms / Complications ... Retinoblastoma #pathophysiology ... #ophthalmology
Diabetic Retinopathy: Pathogenesis and clinical findings Mild Non-proliferative DR • Outpouchings of the weakened capillary walls or
Retinopathy #Diabetes #ophthalmology ... #diagnosis #complications ... #pathophysiology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Signs / Symptoms / Complications ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
#Retinopathy #pathophysiology ... #ophthalmology ... signs #symptoms #complications
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Signs / Symptoms / Complications ... ClosedAngle #Glaucoma #pathophysiology ... #ophthalmology
Keratoconus: Pathogenesis and Clinical Findings Genetics • Family history of keratoconus • Ehlers-Danlos syndrome • Down, Turner,
Signs / Symptoms / Complications ... #Keratoconus #pathophysiology ... #ophthalmology
Retinopathy of Prematurity: Pathogenesis and clinical findings Increased metabolic demand of growing eye -> Excessive VEGF production ->
-> Neovascular complications ... peds #pediatrics #pathophysiology ... #ophthalmology
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