The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview
LH and FSH are required for follicular development and
ovulation -> LH supports ... not implant #MenstrualCycle ... #OvarianCycle #pathophysiology
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
LowAnkleSprain #Sports ... #MSK #orthopedics ... Grades #Diagnosis #pathophysiology
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
conjunctiva) • Bitot's spots ... #Xeropthalmia #pathophysiology ... #ophthalmology
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
-> Cotton-wool spots ... Retinopathy #Diabetes #ophthalmology ... complications #pathophysiology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
-> Cotton-wool Spots ... -> Elschnig's Spots ... #Retinopathy #pathophysiology ... #ophthalmology
Menstrual Cycle Physiology: the Uterine Cycle
The endometrium has receptors for ovarian hormones! Changes in structure and
built up, so a short ... built up, so a short ... fertilized) ovum #MenstrualCycle ... #OvarianCycle #pathophysiology
Age Related Macular Degeneration: Pathogenesis and clinical findings

Photoreceptor atrophy 
-> Extracellular debris (drusen) from RPE atrophy/metabolism
- Faded/blind spots ... MacularDegeneration #pathophysiology ... #ophthalmology
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles
Note: Some charts show different relative levels of
days long) • Starts ... #UterineCycle #MenstrualCycle ... #OvarianCycle #pathophysiology
Hyperopia: Pathogenesis and clinical findings
 • Axial length of eye -> Short axial length of the
length of eye -> Short ... #Hyperopia #pathophysiology ... #ophthalmology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
-> Cherry-red spot ... Occlusion #CRAO #pathophysiology ... #ophthalmology