The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis signs symptoms genetics ophthalmology retinopathy 21hydroxylasedeficiency 21ohd achilles acl anteriorcruciateligament childhood chronic endocrinology hypertensive immunization injury orthopedics otitismedia praderwilli
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Signs/Symptoms/Complications ... fractures • Short ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children) Upper Respiratory Tract Infection: - Bacterial: Streptococcus
Acute Otitis Media ... resolve by 72 hours Complications ... #OtitisMedia #pathophysiology ... symptoms #signs #peds ... #pediatrics
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
warriors") • Acute ... Signs/Symptoms/Complications ... signs #symptoms #pathophysiology ... #msk #orthopedics
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds ... #pediatrics
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
vasoconstrictive • Acute ... -> Cotton-wool Spots ... -> Elschnig's Spots ... #Retinopathy #pathophysiology ... signs #symptoms #complications
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
Tetanus Toxin -> Spores ... lymph -> Koplik's spots ... #Immunization #peds ... #pediatrics #pathophysiology
Retinopathy of Prematurity: Pathogenesis and clinical findings Increased metabolic demand of growing eye -> Excessive VEGF production ->
-> Neovascular complications ... #Prematurity #peds ... #pediatrics #pathophysiology
Isolated Anterior Cruciate Ligament (ACL) Injury: Pathogenesis and clinical findings • Feeling a "pop" • Acute
Feeling a "pop" • Acute ... #ACL #Injury #MSK ... #Sports #pathophysiology
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