The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... spinal artery injury ... function below injury ... weakness and #Acute ... Syndromes #diagnosis #pathophysiology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic ... cells -> Tissue injury ... Pancarditis and valvular injury ... , Carditis #Acute ... RheumaticFever #pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Allergic reaction -> Benign ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
Benign Prostatic ... Hydronephrosis, Acute ... chronic renal injury ... stones #BPH #Benign ... Hyperplasia #Prostate #Pathophysiology
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
Benign Prostatic ... inflammation #BPH #Benign ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology
Acute Otitis Externa (Swimmer’s Ear): Pathogenesis and clinical findings
Pathogens = Pseudomonas aeruginosa (most common opportunistic), Staphylococcus,
Acute Otitis Externa ... hair pins) -> Injury ... #SwimmersEar #pathophysiology
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children)
Upper Respiratory Tract Infection: 
 - Bacterial: Streptococcus
Acute Otitis Media ... #OtitisMedia #pathophysiology ... symptoms #signs #peds
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
metabolites induce injury ... #Immunization #peds ... #pediatrics #pathophysiology
Opioid Withdrawal: Clinical Findings and Complications
Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
life-threatening (exceptions being ... symptoms are more acute ... The less acute behavioral ... Withdrawal #Opiate #Pathophysiology
Isolated Anterior Cruciate Ligament (ACL) Injury: Pathogenesis and clinical findings
 • Feeling a "pop"
 • Acute
Ligament (ACL) Injury ... Feeling a "pop" • Acute ... AnteriorCruciateLigament #ACL #Injury ... #MSK #Sports #pathophysiology