The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
Childhood Immunization ... Tetanus Toxin -> Spores ... lymph -> Koplik's spots ... #Immunization #peds ... #pediatrics #pathophysiology
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
LowAnkleSprain #Sports ... #MSK #orthopedics ... Grades #Diagnosis #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
fractures • Short ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Syndromes #diagnosis #pathophysiology ... signs #symptoms #msk ... #orthopedics #neurology
RICE: Mechanism of Action
Rest (weight bearing or stressful motion discontinued)
Ice (applied to injury)
Compression (wrap applied to
heart) #RICE #Sports ... #pathophysiology ... #mechanism #MSK
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
> Stiffness is short-lived ... Comparison #Versus #MSK ... JointPain #Diagnosis #pathophysiology
Overuse Tendinopathy: Pathogenesis and clinical findings
 • Intrinsic factors: Age, Body weight, Nutrition, Gender, Anatomical variations,
factors: Occupation, Sport ... #Tendinopathy #pathophysiology ... #msk
Isolated Anterior Cruciate Ligament (ACL) Injury: Pathogenesis and clinical findings
 • Feeling a "pop"
 • Acute
#ACL #Injury #MSK ... #Sports #pathophysiology
Posterior Cruciate Ligament (PCL) Injury: Pathogenesis and Clinical Findings
Classification of PCL Iniuries
 • Partial: Translation <
Some sort of end ... #PCL #Injury #MSK ... #Sports #pathophysiology