The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis signs psychiatry sideeffects inhibitors acute alcohol alzheimersdisease anticonvulsants benzodiazepine bulimianervosa bzd caudaequina chronic closedangle dementia erythematosus etoh gastrointestinal genetics
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
Akathisia • SSRI Withdrawal ... Syndrome - ... Serotonin #Inhibitors #Pathophysiology ... #Pharmacology # ... Diagnosis #Signs #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Side Effects Withdrawal ... Vomiting Serotonin Syndrome ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #Pharmacology # ... Diagnosis #Signs #Symptoms
Opioid Withdrawal: Clinical Findings and Complications Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Opioid Withdrawal ... Clinical Findings and Complications ... Note: Opioid withdrawal ... combined with withdrawal ... #Opiate #Pathophysiology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
- Budd Chiari Syndrome ... Gastrointestinal #Complications ... #pathophysiology ... #signs #symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... /Complications: ... #genetics #pathophysiology
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs / Symptoms ... / Complications ... Retinoblastoma #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
Stevens-Johnson Syndrome ... decr intake -> Withdrawal ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
mutations - Down syndrome ... chromosome 21) Signs / Symptoms ... / Complications ... AlzheimersDisease #Dementia #pathophysiology ... diagnosis #signs #symptoms
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... spine Signs / Symptoms ... / Complications ... #MSK #pathophysiology ... #diagnosis #symptoms
Keratoconus: Pathogenesis and Clinical Findings Genetics • Family history of keratoconus • Ehlers-Danlos syndrome • Down, Turner,
Ehlers-Danlos syndrome ... Keratoconus Signs / Symptoms ... / Complications ... #Keratoconus #pathophysiology ... #ophthalmology
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