The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare causes ... Cardiovascular disease ... Overproduction #diagnosis ... endocrinology #pathophysiology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... Alzheimer's (99% of cases ... Alzheimer's (1% of cases ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
hyalinization causes ... BRB breakdown causes ... #Retinopathy #pathophysiology ... #ophthalmology ... #diagnosis #signs
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Inflammatory Disease ... retinal edema caused ... Occlusion #CRAO #pathophysiology ... #ophthalmology ... #diagnosis #signs
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
retinal ischemia causes ... Retinopathy #Diabetes #ophthalmology ... #diagnosis #complications ... #pathophysiology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
• The disease ... • Significant cause ... most frequent cause ... ClosedAngle #Glaucoma #pathophysiology ... #ophthalmology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
findings - For diagnosis ... to 25 for new diagnosis ... their turn • Causes ... BehavioralDisorder #Pathophysiology ... signs #psychiatry #criteria
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
inflammation tends to cause ... interstitial lung disease ... RheumatoidArthritis #RA #pathophysiology ... signs #symptoms #diagnosis
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
epidemiology of this disease ... 40% of patients diagnosed ... history of the disease ... to produce all classes ... Agammaglobulinemia #XLinked #pathophysiology
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
vast majority of cases ... Pseudogout #CPPD #Disease ... Signs #Symptoms #Pathophysiology ... #Diagnosis