The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... like rheumatoid arthritis ... systemic lupus erythematosus ... (SLE) Signs / ... #Symptoms
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... nephrotic/nephritic syndrome ... Arthralgia's (common), arthritis ... Pathophysiology #Diagnosis #Signs ... #Symptoms
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
+ IgG • Immunological ... Gravis, Graves' Disease ... Systemic Lupus Erythematosus ... , Reactive Arthritis ... Stevens-Johnson Syndrome
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Kawasaki Disease ... Findings Diagnostic Criteria ... hands & feet Signs ... /Symptoms/Complications ... : - Coronary Arteritis
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Bitemporal hemianopsia IGF ... Carpal Tunnel Syndrome ... Cardiovascular disease ... Overproduction #diagnosis #signs ... #symptoms #endocrinology