The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology hypersensitivityreaction definitions hypersensitivity reactions anaphylaxis signs symptoms type1 type2 type3 type4 typei typeiii typeiv
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Stevens-Johnson Syndrome ... #Allergic #Reactions ... #Types #Classification
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
Type I Hypersensitivity ... leading to an allergic ... Anaphylaxis #TypeI ... #Type1 #HypersensitivityReaction ... #Allergy #Immunology
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... development of allergen-specific ... Allergic reaction ... Initial exposure to allergen ... Stevens-Johnson Syndrome
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
leading to an allergic ... leading to an allergic ... An allergic reaction ... #Types #Classification ... #Diagnosis #Definitions
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
Type III Hypersensitivity ... sickness #TypeIII #Type3 ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
Type II Hypersensitivity ... cell surfaces #Type2 ... #Type2 #HypersensitivityReaction ... #Allergy #Immunology
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
exposure to a likely allergen ... exposure to known allergen ... pathophysiology #immunology ... #diagnosis #signs
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