The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... Upper Extremity Dysfunction ... deficiencies -> Sphincter dysfunction ... #diagnosis #pathophysiology ... #orthopedics #neurology
Erectile Dysfunction: Pathogenesis

Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
Erectile Dysfunction ... and rigidity Endocrinologic ... Erectile Dysfunction ... #Pathophysiology ... #Urology #Diagnosis
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Vomiting Serotonin Syndrome ... Vertigo, Sexual Dysfunction ... SerotoninNorepinephrine #Inhibitors #Pathophysiology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... Executive planning dysfunction ... concentration • Motor dysfunction ... AlzheimersDisease #Dementia #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... Carpal Tunnel Syndrome ... signs #symptoms #endocrinology ... #pathophysiology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... bladder/bowel dysfunction ... #CaudaEquina #Syndrome ... #MSK #pathophysiology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
• Hypothalamic dysfunction ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings

Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
tumour, stone, BPH ... Incontinence #Mixed #Pathophysiology ... Signs #Symptoms #Urology
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
inflammation #BPH ... Hyperplasia #Prostate #Pathophysiology ... #Pharmacology #Urology
Menstrual Cycle Physiology: Ovarian Cycle – Follicular Phase Explained
Early Follicular Phase (Days 0-5)
 • Granulosa cells
Polycystic Ovarian Syndrome ... #OvarianCycle #pathophysiology ... FollicularPhase #endocrinology