The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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signs symptoms geriatrics incontinence msk retinopathy acute alzheimersdisease bulimianervosa caudaequina chronic diabetic diabeticfoot endocrinology erectile fecal glftap hypertensive injury macroadenoma
Erectile Dysfunction: Pathogenesis Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
trauma, iatrogenic, diabetes ... hyperlipidemia, diabetes ... (penile artery diameter ... #Pathophysiology ... #Urology #Diagnosis
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Signs / Symptoms / Complications ... Executive planning dysfunction ... AlzheimersDisease #Dementia ... #pathophysiology ... #geriatrics #diagnosis
Fecal Incontinence - Pathogenesis and Complications Continence mechanisms are impaired • Local neuronal damage • External and
Pathogenesis and Complications ... Diabetes) • Altered ... (e.g. stroke, dementia ... Incontinence #geriatrics #pathophysiology
Diabetic Retinopathy: Pathogenesis and clinical findings Mild Non-proliferative DR • Outpouchings of the weakened capillary walls or
Diabetic Retinopathy ... #Retinopathy #Diabetes ... #ophthalmology ... #diagnosis #complications ... #pathophysiology
Diabetic Foot: Pathogenesis and clinical findings • Polyol Pathway - Excess glucose enters Polyol pathway ->
Diabetic Foot: Pathogenesis ... increasing cytogenetic dysfunction ... #DiabeticFoot #pathophysiology ... #complications ... #Diabetes
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Signs / Symptoms / Complications ... Hyperprolactinemia • Diabetes ... • Hypothalamic dysfunction ... mnemonic #GLFTAP #pathophysiology
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Signs / Symptoms / Complications ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Signs / Symptoms / Complications ... bladder/bowel dysfunction ... Syndrome #MSK #pathophysiology ... #diagnosis #symptoms
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
cystitis, UTI), diabetes ... Incr PVR if a complication ... Incontinence #Mixed #Pathophysiology ... Signs #Symptoms #Urology ... #Diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Upper Extremity Dysfunction ... deficiencies -> Sphincter dysfunction ... Injury #Syndromes #diagnosis ... #pathophysiology ... #orthopedics #neurology
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