The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis signs symptoms acute cataracts closedangle diabetic diabeticfoot endocrinology erectile glftap incontinence macroadenoma masseffects mixed mnemonic openangle pituitary retinoblastoma retinopathy
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Signs / Symptoms / Complications ... Pseudo-hypopyon • Secondary ... glaucoma • Strabismus ... Retinoblastoma #pathophysiology ... #ophthalmology
Erectile Dysfunction: Pathogenesis Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
trauma, iatrogenic, diabetes ... hyperlipidemia, diabetes ... (penile artery diameter ... #Pathophysiology ... #Urology #Diagnosis
Diabetic Retinopathy: Pathogenesis and clinical findings Mild Non-proliferative DR • Outpouchings of the weakened capillary walls or
Diabetic Retinopathy ... #Retinopathy #Diabetes ... #ophthalmology ... #diagnosis #complications ... #pathophysiology
Diabetic Foot: Pathogenesis and clinical findings • Polyol Pathway - Excess glucose enters Polyol pathway ->
Diabetic Foot: Pathogenesis ... increasing cytogenetic dysfunction ... #DiabeticFoot #pathophysiology ... #complications ... #Diabetes
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle Glaucoma ... present with early glaucoma ... Signs / Symptoms / Complications ... #pathophysiology ... #ophthalmology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Signs / Symptoms / Complications ... Hyperprolactinemia • Diabetes ... • Hypothalamic dysfunction ... mnemonic #GLFTAP #pathophysiology
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
cystitis, UTI), diabetes ... Incr PVR if a complication ... Incontinence #Mixed #Pathophysiology ... Signs #Symptoms #Urology
Secondary Glaucoma: Pathogenesis and Clinical Findings Open-Angle Secondary Glaucoma: • Pre-trabecular defect -> Aqueous outflow is obstructed
Secondary Glaucoma ... Findings Open-Angle Secondary ... Glaucoma: • Pre-trabecular ... #Glaucoma #pathophysiology ... #ophthalmology
Primary Open-Angle Glaucoma: Pathogenesis and Clinical Findings • Risk factors -> Incr IOP, Incr age, African-American
Primary Open-Angle Glaucoma ... family history, diabetes ... central vision #Secondary ... #pathophysiology ... #ophthalmology
Cataract: Pathogenesis and clinical findings Increased Age (most common) -> Ultraviolet light, radiation, toxins ->Denaturation and abnormal
meshwork contact -> Secondary ... angle closure glaucoma ... #cataracts #pathophysiology ... #ophthalmology
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