The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology allergy diagnosis hypersensitivityreaction immunology signs sle symptoms classification definitions hypersensitivity msk musculoskeletal reactions type1 type3 typei types
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... : Gastrointestinal ... the pancreas, Vasculitis ... #Lupus #Erythematosus ... #Complications
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... Ex: Antibiotic allergies ... fever, Urticaria, Allergic ... complexes • Ex: Systemic ... Lupus Erythematosus
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
the cause: • Systemic ... Lupus • Erythematosus ... Serum sickness #TypeIII ... HypersensitivityReaction #Allergy
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Sensitization" to Allergen ... Patient's immune system ... cells recruited Complications ... Anaphylaxis #TypeI
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Osteoporosis #Systemic ... #Lupus #Erythematosus ... Musculoskeletal #Complications
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