The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology allergy diagnosis hypersensitivityreaction immunology signs sle symptoms gastrointestinal hypersensitivity msk musculoskeletal reactions type1 type3 typei typeiii types
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Ex: Antibiotic allergies ... complexes • Ex: Systemic ... Lupus Erythematosus ... #Types #Classification ... #Diagnosis #Definitions
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... distension #Systemic ... #Lupus #Erythematosus ... Gastrointestinal #Complications
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
clinical findings Definition ... leading to an allergic ... Sensitization" to Allergen ... Patient's immune system ... cells recruited Complications
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
clinical findings Definition ... the cause: • Systemic ... Lupus • Erythematosus ... HypersensitivityReaction #Allergy
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Osteoporosis #Systemic ... #Lupus #Erythematosus ... Musculoskeletal #Complications
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