The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology allergy diagnosis hypersensitivityreaction immunology signs sle symptoms classification gastrointestinal hypersensitivity msk musculoskeletal reactions type1 type3 typei typeiii
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Hypersensitivity: Summary Type ... conjunctivitis Type ... complexes • Ex: Systemic ... Lupus Erythematosus ... #Diagnosis #Definitions
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
Type I Hypersensitivity ... clinical findings Definition ... Patient's immune system ... cells recruited Complications ... Anaphylaxis #TypeI
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... distension #Systemic ... #Lupus #Erythematosus ... Gastrointestinal #Complications
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
Type III Hypersensitivity ... clinical findings Definition ... the cause: • Systemic ... Lupus • Erythematosus ... HypersensitivityReaction #Allergy
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Osteoporosis #Systemic ... #Lupus #Erythematosus ... Musculoskeletal #Complications
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