The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis pathophysiology allergy complications erythematosus signs sle symptoms classification comparison definitions degenerative gastrointestinal hypersensitivity hypersensitivityreaction immunology inflammatory jointdisease jointpain musculoskeletal
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... Ex: Antibiotic allergies ... fever, Urticaria, Allergic ... complexes • Ex: Systemic ... Lupus Erythematosus
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... distension #Systemic ... #Lupus #Erythematosus
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Osteoporosis #Systemic ... #Lupus #Erythematosus ... #SLE #MSK #Musculoskeletal
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
the cause: • Systemic ... Lupus • Erythematosus ... HypersensitivityReaction #Allergy
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
is oftentimes systemic ... Rheumatoid arthritis, Lupus ... Comparison #Versus #MSK
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