Localization of Renal Tubular Defects Fanconi Syndrome: Proximal tubule Bartter Syndrome: Thick ascending loop of Henle Gitelman Syndrome: Distal convoluted tubule Liddle Syndrome: Collecting tubule #Liddle #Syndrome #Fanconi #Bartter #Gitelman #Localization #Nephron #Defects #Pathophysiology #Nephrology

Hypercalcemia - Workup and Management #Hypercalcemia #Workup #Diagnosis #Management #Evaluation

Mechanism of malignancy-associated hypercalcemia. Abbreviations: 1,25(OH)2D, 1,25-dihydroxyvitamin D; NHL, non-Hodgkin lymphoma; PTH, parathyroid hormone; PTHrP, PTH-related peptide. #Pathophys #Diagnosis #Hypercalcemia #Malignancy #Mechanism #Frequency #Differential

The principles of insulin adjustment guidance - Schematic diagram of insulin onset and time action profiles - Onset and Duration #Diabetes #Insulin #Analogs #Duration #Peaks #Comparison #Pharmacology #Endocrinology #Timing #Timeline

Summary and links to five landmark trials of intensive control vs standard therapy in DM2: UKPDS 33 - https://www.ncbi.nlm.nih.gov/pubmed/9742976 UKPDS 34 - https://www.ncbi.nlm.nih.gov/pubmed/9742977 VADT - https://www.ncbi.nlm.nih.gov/pubmed/19092145 ADVANCE - https://www.ncbi.nlm.nih.gov/pubmed/18539916 ACCORD - https://www.ncbi.nlm.nih.gov/pubmed/18539917 #EBM #VisualAbstract #Endocrinology #PrimaryCare #Diabetes #DM2 #Type2 #Landmark #Trials #HgbA1c #Targets #Curbsiders

Management of type 2 diabetes in adults: summary of updated NICE guidance #diabetes #type2 #DM2 #management #NICE #guidelines #medications #insulin #BMJ

Diabetes Medication Choice -Diabetes Medication Choice decision aid cards provide information on medications commonly used to treat type 2 diabetes. -The information gathered from relevant research studies is organized into 7 issues that may be of interest to the patient. ** 2018 grepmed editor update ** - To date only metformin, SGLT-i, GLP1 medications have been shown to have cardiovascular/mortality benefits - see https://www.grepmed.com/images/2507 #Management #Diabetes #Type2 #DM2 #PatientInfo #DecisionAid #Medications #Selection #SideEffects #A1c #Reduction #Costs #Pharmacology