Dr. Jorge Cortés @jcortesizaguirr
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diagnosis causes differential hematology abnormal ana antibodies antineutrophil antinuclear coagulation diseases disorders platelet prolonged pt rheumatology thrombocytopenia workup
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... anti-topoisomerase antibody ... 80-90%) > MPO - ANCA ... MPO: 75-80% - ANCA ... #Antinuclear #Antibody
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Abnormal PT and/or aPTT ... typically prolong aPTT ... may prolong the aPTT ... FVIII antibody ... Prolonged PT and aPTT
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
cases: INR/PT, aPTT ... function test, ANA
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