Ravi Singh K @rav7ks
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Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Infection in HIV / AIDS ... Antimicrobial treatment ... differential #diagnosis #AIDS ... opportunistic #InfectiousDiseases
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Histoplasmosis Treatment ... Mucormycosis Treatment ... yeast • At risk: AIDS ... Cryptococcosis Treatment ... ) #Mycoses #InfectiousDiseases
Tuberculosis Testing

LATENT TB
• LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
., AIDS) • < 6 ... LatentTB #ActiveTB #InfectiousDiseases
Blurry Vision - Differential Diagnosis Framework

Anatomical Approach to Eye Disease:
1. Lids/Lashes
2. Extraocular Muscles/Motility
3. Conjunctiva/Sclera
4. Cornea
5. Anterior
Lids/Lashes 2. ... optic disk • HIV/AIDS
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Summary Acute AIDP ... Treatment: • Plasmapheresis ... diagnosis #management #treatment
COVID-19 Diagnosis and Management Summary

 • Clinical Presentation
 • Testing
 • Imaging
 • Laboratory Findings
 •
Laboratory Findings • Treatment ... diagnosis #management #treatment
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis Treatment ... - Symptomatic Treatment ... Immunomodulating Treatments ... exchange - Surgical Treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
six months of treatment ... of HIV/AIDS patients ... be present: • AIDS ... Poor adherence to treatment ... by delaying ART treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
epilepticus Treatment ... underlying cause • Treatment ... Seizures: Treat with AEDs
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
Treatment: • HAART ... treatment • Cognitive ... disorder #dementia #AIDS