Ravi Singh K @rav7ks
1.1M 733 353
Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... • Endogenous reactivation ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... • Endogenous reactivation ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Histoplasmosis Treatment ... change in the lungs ... arthritis, and endocarditis ... nails, bronchi, lungs ... ) #Mycoses #InfectiousDiseases
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... rash) • Heart, lung ... SLE], AOSD) • Infection ... with leukopenia, anemia ... Treatment: • Corticosteroids
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
fibromyalgia) • Infections ... • Libman-Sacks endocarditis ... lymphopenia, low PLT • Anemia ... Chronic B-cell activation ... and leukemia • Lung
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Infectious: • Pre-existing ... , verrucous) - Lung ... Leukocytosis, anemia ... hematuria, + RF Treatment ... Diagnosis #cardiology #infectiousdiseases
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Weight loss • Anemia ... • PET scan - activity ... Hodgkin Lymphoma Treatment ... classification #hematology #oncology
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
with restricted active ... hypothyroidism, infection ... • Normocytic anemia ... TREATMENT: • The ... mainstay of treatment
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
by uncontrolled activation ... Triggers: ▪ Infections ... - Cytopenias (anemia ... absent NK-cell activity ... underlying trigger: Infections