Ravi Singh K @rav7ks
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Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Silicosis • Chronic ... malignancy, and chronic ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Silicosis • Chronic ... malignancy, and chronic ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
polymicrobial infection ... pneumonia • Chronic ... Leukocytosis, anemia ... hemorrhage • Treatment ... several months of treatment
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Immunocompromised status • Chronic ... encounters due to NTM: Chronic ... lung infections ... Bone Marrow - Anemia ... differential #diagnosis #infectiousdiseases
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... weeks without infection ... • Neutropenia, anemia ... microglobulin Treatment ... diagnosis #workup #oncology
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... Abdominal pain, chronic ... 100% of cases), anemia ... #Infections #HIV ... differential #diagnosis #infectiousdiseases
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Infectious: • Pre-existing ... , verrucous) - Lung ... Leukocytosis, anemia ... hematuria, + RF Treatment ... Diagnosis #cardiology #infectiousdiseases
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... Marrow Failure • Chronic ... • Parvovirus infection ... factor (GCSF) treatments ... diagnosis #hematology #oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
fibromyalgia) • Infections ... • Libman-Sacks endocarditis ... lymphopenia, low PLT • Anemia ... with Lupus: • Chronic ... B-cell activation
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... rash) • Heart, lung ... SLE], AOSD) • Infection ... with leukopenia, anemia ... Treatment: • Corticosteroids