Ravi Singh K @rav7ks
1.1M 733 353
Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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diagnosis hematology management aplastic cardiology chronic classification cll differential erythematosus fungal hemeonc hemophagocytic hlh hodgkins leukemia lupus lymphocytic lymphohistiocytosis lymphoma
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Neutropenia - recurrent infections ... Idiopathic • Infections ... Treatment: ... #oncology #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, lung ... SLE], AOSD) • Infection ... with leukopenia, anemia ... Treatment: • Corticosteroids ... #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... change in the lungs ... arthritis, and endocarditis ... nails, bronchi, lungs ... ) #Mycoses #InfectiousDiseases
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Infectious: • Pre-existing ... , verrucous) - Lung ... Leukocytosis, anemia ... hematuria, + RF Treatment ... Diagnosis #cardiology #infectiousdiseases
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... fibromyalgia) • Infections ... • Libman-Sacks endocarditis ... lymphopenia, low PLT • Anemia ... Chronic B-cell activation
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... • Parvovirus infection ... factor (GCSF) treatments ... Syndromes #diagnosis #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... • Neutropenia, anemia ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Treatment ... #oncology #management
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
hypothyroidism, infection ... • Normocytic anemia ... TREATMENT: • The ... mainstay of treatment ... Diagnosis #Management #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
by uncontrolled activation ... Triggers: ▪ Infections ... - Cytopenias (anemia ... underlying trigger: Infections ... Diagnosis #Management #Hematology
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