Ravi Singh K @rav7ks
1.1M 733 352
Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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diagnosis differential hematology management rheumatology hiv syndrome aids cardiology causes fever leukemia pain pulmonary workup abscess activation acute aplastic cell
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... bruising, bleeding, infection ... - infiltrates (anemia ... Leukemia #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
incompetent • CLL ... weeks without infection ... • Neutropenia, anemia ... microglobulin Treatment ... diagnosis #workup #oncology
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Acute bacterial endocarditis ... • Infective endocarditis ... schistosomiasis • Pyemia ... • Gonococcal endocarditis ... Brucellosis • Liver or lung
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Neutropenia - recurrent infections ... Idiopathic • Infections ... Treatment: ... #oncology #hematology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Mycobacteria (NTM) Infections ... infections • ... Advanced HIV (CD4 cell ... Bone Marrow - Anemia ... differential #diagnosis #infectiousdiseases
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... • Parvovirus infection ... factor (GCSF) treatments ... marrow studies Treatment ... diagnosis #hematology #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... • Chronic lung ... disease • Infectious ... lymphocytic interstitial lung ... autoimmune hemolytic anemia
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Infectious: • Pre-existing ... devices (CIED) Non-Infectious ... verrucous) • Lung ... infarction • Infectious ... Leukocytosis, anemia
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... Leukocytosis, anemia ... hemorrhage • Treatment ... continue antibiotic treatment ... several months of treatment
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
• Hemolytic Anemias ... - Pernicious anemia ... Prosthetic valves Lung ... Pneumonia • Other lung ... • Toxins • Infection
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