Ravi Singh K @rav7ks
1.1M 733 352
Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
and Management ... polymicrobial infection ... Leukocytosis, anemia ... Abscess Management ... differential #causes #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... Treatment: ... #oncology #hematology ... #diagnosis #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung ... lymphocytic interstitial lung ... autoimmune hemolytic anemia ... and M panel Management ... hematology #diagnosis #management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... Tuberculosis Treatment ... Initiating Treatment ... TB #Diagnosis #Management ... #Treatment #ActiveTB
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Mycobacteria (NTM) Infections ... Factors For NTM Infections ... infections • ... Bone Marrow - Anemia ... differential #diagnosis #infectiousdiseases
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... Tuberculosis Treatment ... Initiating Treatment ... TB #Diagnosis #Management ... #Treatment #ActiveTB
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Histoplasmosis Treatment ... change in the lungs ... nails, bronchi, lungs ... ) #Mycoses #InfectiousDiseases ... Fungal #Diagnosis #Management
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... 100% of cases), anemia ... cough, myalgia • Lung ... #Infections #HIV ... differential #diagnosis #infectiousdiseases
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... • Parvovirus infection ... factor (GCSF) treatments ... marrow studies Treatment ... diagnosis #hematology #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... • Neutropenia, anemia ... microglobulin Treatment ... diagnosis #workup #oncology