Ravi Singh K @rav7ks
1.1M 733 353
Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Active TB: • HIV ... Treatment: Active ... Initiating Treatment ... : • HIV-infected ... Diagnosis #Management #Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Active TB: • HIV ... Treatment: Active ... Initiating Treatment ... : • HIV-infected ... Diagnosis #Management #Treatment
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Mycobacterium tuberculosis ... mucogenicum • HIV ... Bone Marrow - Anemia ... patients with typical tuberculosis ... differential #diagnosis #infectiousdiseases
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... Mycobacterium tuberculosis ... 100% of cases), anemia ... #Infections #HIV ... differential #diagnosis #infectiousdiseases
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... immunodeficiency virus (HIV ... Treatment: ... #oncology #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... Antimicrobial treatment ... 80% sensitive Tuberculous ... - Hemorrhage, tuberculomas ... opportunistic #InfectiousDiseases
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
polymicrobial infection ... Leukocytosis, anemia ... hemorrhage • Treatment ... continue antibiotic treatment ... several months of treatment
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Infectious: • Pre-existing ... devices (CIED) Non-Infectious ... verrucous) • Lung ... Leukocytosis, anemia ... diagnosis #management #cardiology
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
, verrucous) - Lung ... Leukocytosis, anemia ... hematuria, + RF Treatment ... Differential #Diagnosis #cardiology ... #infectiousdiseases
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
shoulder, and hip ... hypothyroidism, infection ... • Normocytic anemia ... TREATMENT: • The ... mainstay of treatment