Ravi Singh K @rav7ks
1.1M 733 353
Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
: • HIV • Recent ... Treatment: Active ... Initiating Treatment ... : • HIV-infected ... #Management #Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
: • HIV • Recent ... Treatment: Active ... Initiating Treatment ... : • HIV-infected ... #Management #Treatment
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... factor • May cause ... infiltrates, mimicking TB ... ), anemia, arthralgia ... #Infections #HIV
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Mycobacterium tuberculosis ... status NTM Cause ... Kansasii: • Mimics TB ... Bone Marrow - Anemia ... differential #diagnosis #infectiousdiseases
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
polymicrobial infection ... • Most common cause ... Leukocytosis, anemia ... westermani • Other: TB ... #differential #causes
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Neutropenia - recurrent infections ... and petechiae Causes ... Idiopathic • Infections ... Treatment: ... #oncology #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Antimicrobial treatment ... 80% sensitive Tuberculous ... - Hemorrhage, tuberculomas ... Demyelinating disease caused ... opportunistic #InfectiousDiseases
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
• Lymphoma • TB ... Causes: • Still's ... • Disseminated tuberculosis ... Night Sweats: • TB ... Brucellosis • Liver or lung
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
Chronic inflammation causes ... Most Common Causes ... : TB, NTM, PNA ... , CCP, ANCA • HIV ... mycobacteria Treatment
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Infectious: • Pre-existing ... verrucous) • Lung ... Septic Emboli Cause ... Leukocytosis, anemia ... diagnosis #management #cardiology