Ravi Singh K @rav7ks
1.1M 733 353
Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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14 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... anemia Treatment ... #Anemia #oncology ... #hematology #diagnosis
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Endogenous reactivation ... Treatment: Active ... Initiating Treatment ... Inhibitor: • Risk of reactivation ... Diagnosis #Management #Treatment
Tuberculosis Testing

LATENT TB
• LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
decrease the risk for reactivation ... developing active infection ... infection • Recent ... viral infections ... LatentTB #ActiveTB #InfectiousDiseases
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Endogenous reactivation ... Treatment: Active ... Initiating Treatment ... Inhibitor: • Risk of reactivation ... Diagnosis #Management #Treatment
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
e.g., HIV), EBV infection ... Etiology: - Infections ... Solid Tumors • Tuberculosis ... NonHodgkins #comparison #oncology ... #differential #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
result from reactivation ... Antimicrobial treatment ... 80% sensitive Tuberculous ... - Hemorrhage, tuberculomas ... opportunistic #InfectiousDiseases
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Mycobacterium tuberculosis ... other RGM • Plastic ... Hematologic malignancy ... patients with typical tuberculosis ... differential #diagnosis #infectiousdiseases
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... MAS #Macrophage #Activation ... Diagnosis #Management #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... Pure red cell aplasia ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
, breast CA - Hematologic ... Upper respiratory infection ... gastrointestinal infection ... Treatment: - Systemic ... #oncology